トモリ　コウノスケ   友利　幸之介    所属   医療保健学部 リハビリテーション学科　作業療法学専攻    職種   教授
言語種別	日本語
発行・発表の年月	2015
形態種別	学術論文
査読	査読あり
標題	Electrical stimulation of denervated rat skeletal muscle retards trabecular bone loss in early stages of disuse musculoskeletal atrophy
執筆形態	共著
掲載誌名	J Musculo-skelet Neuronal Interact.
掲載区分	国内
巻・号・頁	14,220-8頁
著者・共著者	Tamaki H, Tomori K, Yotani K, Ogita F, Sugawara K, Kirimto H, Onishi H, Yamamoto N, Kasuga N
概要	We aimed to determine the intensity of muscle stimulation required to prevent structural failure as well as bone and skeletal muscle loss after denervation-induced disuse. Seven-week-old rats were randomly assigned to age-matched groups comprising control (CON), sciatic nerve denervation (DN) or direct electrical stimulation (ES) one day later (after denervation) with 4, 8 and 16 mA at 10 Hz for 30 min/day, six days/week, for one or three weeks. High-intensity electrical muscle stimulation delayed trabecular bone loss during the early stages (one week after DN) of musculoskeletal atrophy due to disuse.