ゴトウ サキ
後藤 早希 所属 応用生物学部 応用生物学科 職種 助教 |
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言語種別 | 英語 |
発行・発表の年月 | 2022/02 |
形態種別 | 学術論文 |
査読 | 査読あり |
標題 | Enhanced production of (R)-3-hydroxybutyrate oligomers by coexpression of molecular chaperones in recombinant Escherichia coli harboring a polyhydroxyalkanoate synthase derived from Bacillus cereus YB-4 |
執筆形態 | 共著 |
掲載誌名 | Microorganisms |
掲載区分 | 国外 |
出版社・発行元 | MDPI |
巻・号・頁 | 10(2),pp.458 |
担当区分 | 筆頭著者 |
著者・共著者 | Saki Goto, Yuki Miyahara, Seiichi Taguchi, Takeharu Tsuge and Ayaka Hiroe |
概要 | In addition to its potential value as an antibacterial substance, the (R)-3-hydroxybutyrate oligomer (3HBO) also holds promise as a building block for various polymers. To construct an efficient 3HBO production system, we examined the coexpression of molecular chaperones and a polyhydroxyalkanoate (PHA) synthase derived from Bacillus cereus YB-4. As a result, coexpression of chaperone proteins enhanced both the amount of active PHA synthase and the production yield of 3HBO. |
DOI | 10.3390/microorganisms10020458 |
外部リンクURL | https://doi.org/10.3390/microorganisms10020458 |