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言語種別	英語
発行・発表の年月	2016/08
形態種別	学術論文
査読	査読あり
標題	Fluorescence detection of single-nucleotide differences using aptamer-forming binary DNA probes.
執筆形態	共著
掲載誌名	Analyst
掲載区分	国外
出版社・発行元	Royal Society of Chemistry
巻・号・頁	141(21),pp.6087-6092
著者・共著者	S. Kamoto, M. Hyuga
概要	We report a simple method for fluorescence detection of single-nucleotide alterations in a long target DNA, which is based on the formation of a three-way-junction-structured cholic-acid-binding DNA aptamer by the hybridization of the target with binary DNA probes. The new method was successfully exploited for SNP genotyping of human CYP2C19 gene.
DOI	10.1039/C6AN00912C