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言語種別	日本語
発行・発表の年月	2016/02
形態種別	学術論文
査読	査読あり
標題	Light-up fluorophore–DNA aptamer pair for label-free turn-on aptamer sensors
執筆形態	共著
掲載誌名	Chemical Communications
掲載区分	国外
出版社・発行元	Royal Society of Chemistry
巻・号・頁	52(21),4041-4044頁
著者・共著者	Ippei Shimada, Ryota Kimura, Masumi Hyuga
概要	We developed a light-up fluorophore–DNA aptamer pair for label-free aptamer sensors that fluoresce upon binding to the analyte. A 42mer DNA aptamer binding to the environment-sensitive fluorophore, dapoxyl, which increased the fluorescence by more than 700-fold upon binding, was successfully used to construct aptamer sensors by fusion with analyte-binding DNA aptamers.
DOI	10.1039/C5CC08816J
論文（査読付）ファイル	DOWNLOAD