カトウ テル
加藤 輝 所属 応用生物学部 応用生物学科 職種 教授 |
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言語種別 | 英語 |
発行・発表の年月 | 2014/03 |
形態種別 | 学術論文 |
査読 | 査読あり |
標題 | Sequence-selective Modification of DNA Cytosine by Using Junction-forming DNA Probes and Its Application to the Detection of Single Cytosine Methylation. |
執筆形態 | 共著 |
掲載誌名 | Analytical Sciences |
出版社・発行元 | The Japan Society for Analytical Chemistry |
巻・号・頁 | 30(3),pp.371-376 |
著者・共著者 | Kenta Takanashi |
概要 | Methylated DNA plays an important role in epigenetic gene regulation, and could therefore serve as a potentially promising biomarker for the diagnosis of cancer and other diseases. Therefore, the development of a simple method for analyzing cytosine methylation in a target gene is required. Here, we report on a simple polymerase chain reaction (PCR)-based assay for 'pinpoint' methylation analysis. |
DOI | http://dx.doi.org/10.2116/analsci.30.371 |