カトウ テル
  加藤 輝
   所属   応用生物学部 応用生物学科
   職種   教授
言語種別 英語
発行・発表の年月 2014/03
形態種別 学術論文
査読 査読あり
標題 Sequence-selective Modification of DNA Cytosine by Using Junction-forming DNA Probes and Its Application to the Detection of Single Cytosine Methylation.
執筆形態 共著
掲載誌名 Analytical Sciences
出版社・発行元 The Japan Society for Analytical Chemistry
巻・号・頁 30(3),pp.371-376
著者・共著者 Kenta Takanashi
概要 Methylated DNA plays an important role in epigenetic gene regulation, and could therefore serve as a potentially promising biomarker for the diagnosis of cancer and other diseases. Therefore, the development of a simple method for analyzing cytosine methylation in a target gene is required. Here, we report on a simple polymerase chain reaction (PCR)-based assay for 'pinpoint' methylation analysis.
DOI http://dx.doi.org/10.2116/analsci.30.371